(University of Texas at Austin, Texas Advanced Computing Center) Scientists used supercomputers to find a mechanism that activates cell mutations found in about 50 percent of melanomas. An October 2019 Science study determined the structure and activation mechanism of the protein complex B-Raf linked to melanoma. XSEDE allocations on Stampede2 of TACC and Bridges at Pittsburgh Supercomputing Center modeled the B-Raf protein and other proteins in the pathway linked to skin cancer. The study can help in the design of better drugs.
Original source: https://www.eurekalert.org/pub_releases/2019-12/uota-scm121719.php