(Data Science Institute at Columbia) Depression is a debilitating illness that affects more than 350 million people. About half of the people who take antidepressants, however, do not respond to the treatment. This team is thus trying to understand the molecular mechanisms of such treatment resistance. Ultimately, they would like to be able to predict which people will respond to antidepressant drugs before they begin treatment, and to develop treatments that can circumvent antidepressant resistance in the millions of people who do not respond to antidepressants.
Original source: https://www.eurekalert.org/pub_releases/2019-03/dsia-ctd031319.php